Phytocannabinoids in Cannabis
In an earlier article, you may have learned that an easy way to separate Hemp and Marijjuana is that Hemp is a cannabis flower, with less than .3% THC. Marijuana is a cannabis flower with more than .3% THC. THC (Tetrahydrocannabinol) is the primary phytocannabinoid found in cannabis which is responsible for the psychoactive component of the plant. Some hemp, and marijuana can smell, and look nearly identical! This means Hemp is Cannabis but not Marijuana!
There are a range of several beneficial phytocannabinoids found in cannabis. Phytocannabinoids in cannabis can aid with discomforts from pain, insomnia, appetite, or lack thereof by binding to receptors in your endocannabinoid system. CB1 receptors and CB2 receptors are the primary receptors in your endocannabinoid system. CB1 receptors are mostly located in the brain and nervous system, but also throughout the body. CB2 receptors are found throughout the body on cells associated with the immune system. At Carolina Hemp Hut stores, you can find products with isolated cannabinoids and joyous blends with multiple cannabinoids!
Cannabidiol is found in hemp with a low percentage of THC and a higher percentage of CBD. Cannabidiol bonds to serotonin receptors which provides a therapeutic effect for anxiety. Vanilloid Receptors which regulate pain perception, inflammation, and body temperature, also bond to CBD. CBD activates PPAR-receptors that regulate genes responsible for the homeostasis of different metabolic functions from lipid uptake to insulin sensitivity, and energy. CBD can be great for maintaining balance in the body. Cannabidiol can be used in the forms of topicals, ingestibles, sublingual drops, and smokable hemp.
Tetrahydrocannabinol (THC) is the most well known cannabinoid found in cannabis. THC is the psychoactive component in cannabis. THC has been discovered to have several isomers, and variations found in cannabis. An isomer is a chemical compound that is identical in structure to another.
This popular cannabinoid is primarily responsible for the “high’ that many cannabis enthusiasts love.
Delta 8 THC is a THC isomer with the double bond pair on the upper left portion of the Hydrogen bond. Delta 8 THC and the other delta variants of THC are identical in chemical structure. As for the effects, when Delta 8 THC is ingested it is more calming, relaxing, and soothing. Consumers have mentioned more of a “body high,” and claim to have improved sleep. Delta 8 THC when vaped or smoked has the potential to be more uplifting, and invigorating when paired with terpenes that are more sativa leaning.
The original (OG) THC most commonly referred to as plainly THC. Delta 9 THC is the most intense, “most potent high” feeling THC. Delta 9 THC is the most abundant phytocannabinoid in marijuana. This compound is both mentally stimulating while also great for body relaxation. Delta 9 THC can be used to help with a plethora of ailments from inflammation to nausea, seizures, to appetite. As with Delta 8, Terpenes play a huge role in strain expression and how the “high” feels. Flowers and concentrates with Sativa or Indica leaning terpenes will express as such, and can lead to a variety of experiences from energized to couch-locked, and even somewhere in between.
My personal favorite of the Delta THC Isomers is Delta 10 THC. I’ve used words like energizing to describe something as sativa leaning. Delta 10 when ingested is a true sativa feel. Delta 10 THC is absolutely splendid for daytime use, as it can help boost creativity, energy, and mood. Slightly less intense than Delta 8 THC, Delta 10 THC may provide clarity, and be more focus boosting! Customer feedback at Carolina Hemp Hut has reinforced my opinion of Delta 10 being the best aid to knock out any cumbersome chores!
Tetrahydrocannabivarin, say that 5 times fast. THC-V is best known for 5 things; Appetite suppression, Type II Diabetes, PTSD, Bone Density and Growth, and Anxiety.
There is no such thing as a perfect weight loss drug, a calorie deficit is the only way to lose fat. With that said, THC-V can help suppress appetite by increasing satiety, and up-regulating your energy metabolism.
THC-O or it’s full name THC-O-acetate ester is a synthesized hemp derived cannabis compound, and cannot be naturally found in cannabis. The safe production of THC-O products requires special equipment designed for volatile and flammable chemicals. The effects of THC-O vary from person to person. Some say THC-O is far more potent than Delta 9 THC, others have said it is a more spiritual/psychedelic experience. THC-O will have a delayed onset effect due to the compound metabolizing like an edible, even when inhaled.
Tetrahydrocannabiphorol AKA THC-P AKA (-)-Trans-Δ9-tetrahydrocannabinol is one of the newest natural cannabinoids found in cannabis. It is an analog of THC that has the cannabis industry going berserk. This marvel is said to be 33 times more active than Delta 9 THC towards CB1 receptors. This hyper activity towards the CB1 receptors can cause a more intense/intoxicating euphoric high.
CBG, CBC, and CBN
The Mother Cannabinoid, CBG serves as a precursor molecule for other more abundant cannabinoids. There are studies showing that CBG may have therapeutic potential for neurological disorders, may treat inflammatory bowel disease, and CBG studies also show antibacterial activity. There is strong evidence for CBG as an anti-inflammatory and an analgesic targeting both pain and inflammation more directly. Cannabigerol can be taken as a sublingual drop, or edible in Carolina Hemp Hut Stores.
Much like cannabigerol (CBG), cannabichromene (CBC) selectively reduces inflammation. When paired with Tetrahydrocannabinol (THC) , the effects of the THC are elevated. CBC is found in an Equilibrium Blend by One Source botanicals, paired with hemp derived Delta 9 THC, Delta 8 THC, CBD, and CBG in a yummy gummy form!
The first cannabinoid to be identified and isolated from cannabis is cannabinol (CBN). CBN is a byproduct of THC degradation. CBN studies though inconclusive show benefits as a sedative for sleep, an anti-inflammatory, and antibacterial. According to sciencedirect.com “CBN additionally stimulates recruitment of quiescent mesenchymal stem cells in marrow (10 μM) promoting bone formation (Scutt & Williamson, 2007) and can affect breast cancer resistance proteins”
Hexahydrocannabinol(HHC) is a hydrogenation derivative of Tetrahydrocannabinol(THC).HHC is naturally found in the stems, and buds of cannabis. Similar to THC it can have analgesic effects, as well as psychotropic effects. HHC has a weaker affinity to CB1 receptors, and therefore has been reported to be a less intense “high” than THC. There is some anecdotal evidence to suggest HHC may evade a drug test. HHC has been advertised to allegedly not metabolize into 11-Hydroxy-THC which is a common drug test metabolite, therefore should not pop positive. I caution to not avoid a drug test by consuming solely HHC , it is not worth the risk of failure.
That’s a Wrap (Hemp Wrap)!
If you’ve stuck with me this far, then you have learned a TON about phytocannabinoids in cannabis. Cannabis has been used as medicine for centuries and the compounds provided here are part of the success story!
The medicinal benefits are extensive, and research is constantly bringing forth newer uses, and newer cannabinoids! With all this information where do I find these cannabinoids? Where can I buy it? I’ve gained a lot of experience with cannabis products and their results.
I work at Carolina Hemp Hut, a retail store that has the largest selection of cannabis products and cannabinoids in North Carolina. Visit the website to explore the wonderful world of cannabis and how it can help you with your health and happiness.
Cannabis Consultant and Sr. Budtender
Carlos approaches cannabis products from a very common view point. As an adult, he learned “adulting” is not easy. When dealing with hardships that are common to the burdens of everyday life, he discovered how cannabis helps ease away the anxiety that normally builds to a breaking point. He delved into learning more and experiencing more in the process. This journey helped him become well-seasoned with an array of cannabis forms and uses.
How CBD Works (projectcbd.org)